Coupling of the cell cycle and myogenesis through the cyclin D1-dependent interaction of MyoD with cdk4.

Proliferating myoblasts express the muscle determination factor, MyoD, throughout the cell cycle in the absence of differentiation. Here we show that a mitogen-sensitive mechanism, involving the direct interaction between MyoD and cdk4, restricts myoblast differentiation to cells that have entered i...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, J M, Wei, Q, Zhao, X, Paterson, B M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171185/
https://ncbi.nlm.nih.gov/pubmed/10022835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.4.926
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