Učitavanje...
Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2.
We show here that Vav-2, a member of the Vav family of oncoproteins, acts as a guanosine nucleotide exchange factor (GEF) for RhoG and RhoA-like GTPases in a phosphotyrosine-dependent manner. Moreover, we show that Vav-2 oncogenic activation correlates with the acquisition of phosphorylation-indepen...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1998
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171007/ https://ncbi.nlm.nih.gov/pubmed/9822605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.22.6608 |
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