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The plasmid replicon of EBV consists of multiple cis-acting elements that facilitate DNA synthesis by the cell and a viral maintenance element.

Plasmids containing oriP, the plasmid origin of Epstein-Barr virus (EBV), are replicated stably in human cells that express a single viral trans-acting factor, EBNA-1. Unlike plasmids of other viruses, but akin to human chromosomes, oriP plasmids are synthesized once per cell cycle, and are partitio...

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Hlavní autoři: Aiyar, A, Tyree, C, Sugden, B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170964/
https://ncbi.nlm.nih.gov/pubmed/9799247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.21.6394
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