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Krüppel acts as a developmental switch gene that mediates Notch signalling-dependent tip cell differentiation in the excretory organs of Drosophila.

Cell proliferation in the excretory organs of Drosophila, the Malpighian tubules (MT), is under the control of a neural tip cell. This unique cell is singled out from equivalent MT primordial cells in response to Notch signalling. We show that the gene Krüppel (Kr), best known for its segmentation f...

詳細記述

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書誌詳細
主要な著者: Hoch, M, Jäckle, H
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170904/
https://ncbi.nlm.nih.gov/pubmed/9755176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.19.5766
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