Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum.

Members of the Plasmodium falciparum var gene family encode clonally variant adhesins, which play an important role in the pathogenicity of tropical malaria. Here we employ a selective panning protocol to generate isogenic P.falciparum populations with defined adhesive phenotypes for CD36, ICAM-1 an...

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Main Authors: Scherf, A, Hernandez-Rivas, R, Buffet, P, Bottius, E, Benatar, C, Pouvelle, B, Gysin, J, Lanzer, M
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170867/
https://ncbi.nlm.nih.gov/pubmed/9736619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.18.5418
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