Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains.

T-cell receptors (TCRs) upon binding to peptide-MHC ligands transduce signals in T lymphocytes. Tyrosine phosphorylations in the cytoplasmic domains of the CD3 (gammadeltaepsilon) and zeta subunits of the TCR complex by Src family kinases initiate the signaling cascades via docking and activation of...

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Detalhes bibliográficos
Main Authors: Montixi, C, Langlet, C, Bernard, A M, Thimonier, J, Dubois, C, Wurbel, M A, Chauvin, J P, Pierres, M, He, H T
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170860/
https://ncbi.nlm.nih.gov/pubmed/9736612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.18.5334
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