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Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast.

Although iron is an essential nutrient, it is also a potent cellular toxin, and the acquisition of iron is a highly regulated process in eukaryotes. In yeast, iron uptake is homeostatically regulated by the transcription factor encoded by AFT1. Expression of AFT1-1(up), a dominant mutant allele, res...

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Detalhes bibliográficos
Main Authors: Philpott, C C, Rashford, J, Yamaguchi-Iwai, Y, Rouault, T A, Dancis, A, Klausner, R D
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170830/
https://ncbi.nlm.nih.gov/pubmed/9724638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.17.5026
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