Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast.

Although iron is an essential nutrient, it is also a potent cellular toxin, and the acquisition of iron is a highly regulated process in eukaryotes. In yeast, iron uptake is homeostatically regulated by the transcription factor encoded by AFT1. Expression of AFT1-1(up), a dominant mutant allele, res...

Full description

Saved in:
Bibliographic Details
Main Authors: Philpott, C C, Rashford, J, Yamaguchi-Iwai, Y, Rouault, T A, Dancis, A, Klausner, R D
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170830/
https://ncbi.nlm.nih.gov/pubmed/9724638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.17.5026
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items