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Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast.
Although iron is an essential nutrient, it is also a potent cellular toxin, and the acquisition of iron is a highly regulated process in eukaryotes. In yeast, iron uptake is homeostatically regulated by the transcription factor encoded by AFT1. Expression of AFT1-1(up), a dominant mutant allele, res...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1998
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170830/ https://ncbi.nlm.nih.gov/pubmed/9724638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.17.5026 |
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