DPM2 regulates biosynthesis of dolichol phosphate-mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate.

Biosynthesis of glycosylphosphatidylinositol and N-glycan precursor is dependent upon a mannosyl donor, dolichol phosphate-mannose (DPM). The Thy-1negative class E mutant of mouse lymphoma and Lec15 mutant Chinese hamster ovary (CHO) cells are incapable of DPM synthesis. The class E mutant is defect...

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Hlavní autoři: Maeda, Y, Tomita, S, Watanabe, R, Ohishi, K, Kinoshita, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170821/
https://ncbi.nlm.nih.gov/pubmed/9724629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.17.4920
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