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Role of the DnaK and HscA homologs of Hsp70 chaperones in protein folding in E.coli.

Folding of newly synthesized cytosolic proteins has been proposed to require assistance by Hsp70 chaperones. We investigated whether two Hsp70 homologs of Escherichia coli, DnaK and HscA, have this role in vivo. Double mutants lacking dnaK and hscA were viable and lacked defects in protein folding a...

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Detalhes bibliográficos
Main Authors: Hesterkamp, T, Bukau, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170811/
https://ncbi.nlm.nih.gov/pubmed/9707441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.16.4818
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