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AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition.
In order to identify key structural determinants for ligand recognition, we subjected the ligand-binding domain of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-selective glutamate receptor GluR-D subunit to site-directed mutagenesis. Based on the analysis of the [3H]AMPA-bind...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170799/ https://ncbi.nlm.nih.gov/pubmed/9707429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.16.4704 |
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