Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-lambda, epsilon and zeta.

The implication of protein kinase C (PKC) isoforms cPKC-alpha, nPKC-epsilon, aPKC-lambda and aPKC-zeta in the transcriptional activation of a c-fos promoter-driven CAT-reporter construct by transforming Ha-Ras has been investigated. This was achieved by employing antisense constructs encoding RNA di...

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Autores principales: Kampfer, S, Hellbert, K, Villunger, A, Doppler, W, Baier, G, Grunicke, H H, Uberall, F
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170737/
https://ncbi.nlm.nih.gov/pubmed/9670019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.4046
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