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Interaction of mitochondrial targeting signals with acidic receptor domains along the protein import pathway: evidence for the 'acid chain' hypothesis.

Mitochondrial precursor proteins with basic targeting signals may be transported across the outer membrane by sequential binding to acidic receptor sites of increasing affinity. To test this 'acid chain' hypothesis, we assayed the interaction of mitochondrial precursors with three acidic r...

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Autors principals: Komiya, T, Rospert, S, Koehler, C, Looser, R, Schatz, G, Mihara, K
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170724/
https://ncbi.nlm.nih.gov/pubmed/9670006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.3886
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