lambda bar minigene-mediated inhibition of protein synthesis involves accumulation of peptidyl-tRNA and starvation for tRNA.

Expression of the bacteriophage lambda two-codon, AUG AUA, barI minigene (bar+) leads to the arrest of protein synthesis in cells defective in peptidyl-tRNA hydrolase (Pth). It has been hypothesized that translation of the bar+ transcript provokes premature release and accumulation of peptidyl-tRNA...

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Hlavní autoři: Hernández-Sánchez, J, Valadez, J G, Herrera, J V, Ontiveros, C, Guarneros, G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170711/
https://ncbi.nlm.nih.gov/pubmed/9649445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.13.3758
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