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Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages.

Tat stimulates human immunodeficiency virus type 1 (HIV-1) transcription elongation through recognition of the transactivation response (TAR) RNA stem-loop structure at the 5' end of nascent viral transcripts. Recently, a human transcription elongation factor P-TEFb, consisting of CDK9 kinase,...

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Autori principali: Zhou, Q, Chen, D, Pierstorff, E, Luo, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170704/
https://ncbi.nlm.nih.gov/pubmed/9649438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.13.3681
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