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Embryonic lethality and abnormal cardiac myocytes in mice lacking ryanodine receptor type 2.
The ryanodine receptor type 2 (RyR-2) functions as a Ca2+-induced Ca2+ release (CICR) channel on intracellular Ca2+ stores and is distributed in most excitable cells with the exception of skeletal muscle cells. RyR-2 is abundantly expressed in cardiac muscle cells and is thought to mediate Ca2+ rele...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170669/ https://ncbi.nlm.nih.gov/pubmed/9628868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.12.3309 |
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