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Transposase makes critical contacts with, and is stimulated by, single-stranded DNA at the P element termini in vitro.

P elements transpose by a cut-and-paste mechanism. Donor DNA cleavage mediated by transposase generates 17 nucleotide (nt) 3' single-strand extensions at the P element termini which, when present on oligonucleotide substrates, stimulate both the strand-transfer and disintegration reactions in v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beall, E L, Rio, D C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170556/
https://ncbi.nlm.nih.gov/pubmed/9524133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.7.2122
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