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Disruption of the HSF3 gene results in the severe reduction of heat shock gene expression and loss of thermotolerance.
The vertebrate genome encodes a family of heat shock factors (HSFs 1-4) of which the DNA-binding and transcriptional activities of HSF1 and HSF3 are activated upon heat shock. HSF1 has the properties of a classical HSF and exhibits rapid activation of DNA-binding and transcriptional activity upon ex...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170522/ https://ncbi.nlm.nih.gov/pubmed/9501096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.6.1750 |
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