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Roles of the helicase and primase domain of the gene 4 protein of bacteriophage T7 in accessing the primase recognition site.

The 63 kDa gene 4 protein of bacteriophage T7 provides both helicase and primase activities. The C-terminal helicase domain of the gene 4 protein is responsible for DNA-dependent NTP hydrolysis and for hexamer formation, whereas the N-terminal primase domain contains the zinc motif that is, in part,...

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Main Authors: Kusakabe, T, Baradaran, K, Lee, J, Richardson, C C
Formato: Artigo
Idioma:Inglês
Publicado: 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170502/
https://ncbi.nlm.nih.gov/pubmed/9482751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.5.1542
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