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Ca2+-induced exocytosis in individual human neutrophils: high- and low-affinity granule populations and submaximal responses.

We have investigated Ca2+-induced exocytosis from human neutrophils using the whole cell patch-clamp capacitance technique. Microperfusion of Ca2+ buffer solutions (<30 nM to 5 mM free Ca2+) through the patch-clamp pipette revealed a biphasic activation of exocytosis by Ca2+. The first phase was...

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Detalhes bibliográficos
Main Authors: Nüsse, O, Serrander, L, Lew, D P, Krause, K H
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170476/
https://ncbi.nlm.nih.gov/pubmed/9482725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.5.1279
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