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Inosine exists in mRNA at tissue-specific levels and is most abundant in brain mRNA.
The general view that mRNA does not contain inosine has been challenged by the discovery of adenosine deaminases that act on RNA (ADARs). Although inosine monophosphate (IMP) cannot be detected in crude preparations of nucleotides derived from poly(A)+ RNA, here we show it is readily detectable and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1998
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170460/ https://ncbi.nlm.nih.gov/pubmed/9463389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.4.1120 |
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