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Ca2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor.

alpha-Latrotoxin (alpha-LTX) induces exocytosis of small synaptic vesicles (SSVs) in neuronal cells both by a calcium-independent mechanism and by opening cation-permeable pores. Since the basic molecular events regulating exocytosis in neurons and endocrine cells may be similar, we have used the ex...

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Detalhes bibliográficos
Main Authors: Lang, J, Ushkaryov, Y, Grasso, A, Wollheim, C B
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170414/
https://ncbi.nlm.nih.gov/pubmed/9450990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.3.648
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