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The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen.

The three-dimensional structure of human procarboxypeptidase A2 has been determined using X-ray crystallography at 1.8 A resolution. This is the first detailed structural report of a human pancreatic carboxypeptidase and of its zymogen. Human procarboxypeptidase A2 is formed by a pro-segment of 96 r...

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Bibliografische gegevens
Hoofdauteurs: García-Sáez, I, Reverter, D, Vendrell, J, Avilés, F X, Coll, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170294/
https://ncbi.nlm.nih.gov/pubmed/9384570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.23.6906
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