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Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8.
Transcription factors of the Pax family bind to their target genes via the paired domain which is known to be composed of two subdomains each recognizing distinct half-sites in adjacent major grooves of the DNA helix. We now demonstrate that the mammalian Pax8 gene gives rise, by alternative mRNA sp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1997
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170283/ https://ncbi.nlm.nih.gov/pubmed/9362493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.22.6793 |
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