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The C-propeptide domain of procollagen can be replaced with a transmembrane domain without affecting trimer formation or collagen triple helix folding during biosynthesis.

The folding and assembly of procollagen occurs within the cell through a series of discrete steps leading to the formation of a stable trimer consisting of three distinct domains: the N-propeptide, the C-propeptide and the collagen triple helix flanked at either end by short telopeptides. We have es...

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Détails bibliographiques
Auteurs principaux: Bulleid, N J, Dalley, J A, Lees, J F
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170274/
https://ncbi.nlm.nih.gov/pubmed/9362484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.22.6694
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