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Intramolecular synapsis of duplex DNA by vaccinia topoisomerase.
Complexes formed by vaccinia topoisomerase I on plasmid DNA were visualized by electron microscopy. The enzyme formed intramolecular loop structures in which non-contiguous DNA segments were synapsed within filamentous protein stems. At high enzyme concentrations the DNA appeared to be zipped up wit...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170262/ https://ncbi.nlm.nih.gov/pubmed/9351838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.21.6584 |
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