The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.

समान संसाधन

• Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1.
  द्वारा: Rothwell, D G, और अन्य
  प्रकाशित: (1996)
• Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding
  द्वारा: Rothwell, D. G., और अन्य
  प्रकाशित: (2000)
• Role of the HAP1 protein in repair of oxidative DNA damage and regulation of transcription factors.
  द्वारा: Barzilay, G., और अन्य
  प्रकाशित: (1996)
• Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.
  द्वारा: Wilson, D M, और अन्य
  प्रकाशित: (1997)
• Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity.
  द्वारा: Barzilay, G, और अन्य
  प्रकाशित: (1995)