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Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade.

The Epstein-Barr virus latent membrane protein-1 (LMP-1) is an integral membrane protein which transforms fibroblasts and is essential for EBV-mediated B-cell immortalization. LMP-1 has been shown to trigger cellular NF-kappa B activity which, however, cannot fully explain the oncogenic potential of...

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Autores principales: Kieser, A, Kilger, E, Gires, O, Ueffing, M, Kolch, W, Hammerschmidt, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170253/
https://ncbi.nlm.nih.gov/pubmed/9351829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.21.6478
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