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Plasmid rolling circle replication: identification of the RNA polymerase-directed primer RNA and requirement for DNA polymerase I for lagging strand synthesis.

Plasmid rolling circle replication involves generation of single-stranded DNA (ssDNA) intermediates. ssDNA released after leading strand synthesis is converted to a double-stranded form using solely host proteins. Most plasmids that replicate by the rolling circle mode contain palindromic sequences...

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Main Authors: Kramer, M G, Khan, S A, Espinosa, M
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170209/
https://ncbi.nlm.nih.gov/pubmed/9312036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.18.5784
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