Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

The small G protein Rap2A has been crystallized in complex with GDP, GTP and GTPgammaS. The Rap2A-GTP complex is the first structure of a small G protein with its natural ligand GTP. It shows that the hydroxyl group of Tyr32 forms a hydrogen bond with the gamma-phosphate of GTP and with Gly13. This...

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Detalhes bibliográficos
Main Authors: Cherfils, J, Ménétrey, J, Le Bras, G, Janoueix-Lerosey, I, de Gunzburg, J, Garel, J R, Auzat, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170190/
https://ncbi.nlm.nih.gov/pubmed/9312017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.18.5582
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