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A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family.

The ActA protein of the intracellular pathogen Listeria monocytogenes induces a dramatic reorganization of the actin-based cytoskeleton. Two profilin binding proteins, VASP and Mena, are the only cellular proteins known so far to bind directly to ActA. This interaction is mediated by a conserved mod...

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Библиографические подробности
Главные авторы: Niebuhr, K, Ebel, F, Frank, R, Reinhard, M, Domann, E, Carl, U D, Walter, U, Gertler, F B, Wehland, J, Chakraborty, T
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170174/
https://ncbi.nlm.nih.gov/pubmed/9312002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.17.5433
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