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Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product.

The expression of the high mobility group I (HMGI)-C chromatin component was shown previously to be essential for the establishment of the neoplastic phenotype in retrovirally transformed thyroid cell lines. To identify possible targets of the HMGI-C gene product, we have analyzed the AP-1 complex i...

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Autors principals: Vallone, D, Battista, S, Pierantoni, G M, Fedele, M, Casalino, L, Santoro, M, Viglietto, G, Fusco, A, Verde, P
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170163/
https://ncbi.nlm.nih.gov/pubmed/9311991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.17.5310
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