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Bivalence of EGF-like ligands drives the ErbB signaling network.
Signaling by epidermal growth factor (EGF)-like ligands is mediated by an interactive network of four ErbB receptor tyrosine kinases, whose mechanism of ligand-induced dimerization is unknown. We contrasted two existing models: a conformation-driven activation of a receptor-intrinsic dimerization si...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1997
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170129/ https://ncbi.nlm.nih.gov/pubmed/9305636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.16.4938 |
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