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The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry.
The Bcl-2 family of proteins regulate apoptosis, some antagonizing cell death and others facilitating it. It has recently been demonstrated that Bcl-2 not only inhibits apoptosis but also restrains cell cycle entry. We show here that these two functions can be genetically dissociated. Mutation of a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1997
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170089/ https://ncbi.nlm.nih.gov/pubmed/9303307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.15.4628 |
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