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Why is the initiation nick site of an AT-rich rolling circle plasmid at the tip of a GC-rich cruciform?
pT181 and other closely related rolling circle plasmids have the nicking site for initiation of replication between the arms of a GC-rich inverted repeat sequence adjacent to the binding site for the dimeric initiator protein. Replication is initiated by the initiator-induced extrusion of this seque...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170072/ https://ncbi.nlm.nih.gov/pubmed/9250690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.14.4456 |
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