Subtle hydrophobic interactions between the seventh residue of the zinc finger loop and the first base of an HGATAR sequence determine promoter-specific recognition by the Aspergillus nidulans GATA factor AreA.

A change of a universally conserved leucine to valine in the DNA-binding domain of the GATA factor AreA results in inability to activate some AreA-dependent promoters, including that of the uapA gene encoding a specific urate-xanthine permease. Some other AreA-dependent promoters become able to func...

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Autors principals: Ravagnani, A, Gorfinkiel, L, Langdon, T, Diallinas, G, Adjadj, E, Demais, S, Gorton, D, Arst, H N, Scazzocchio, C
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170021/
https://ncbi.nlm.nih.gov/pubmed/9233807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.13.3974
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