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Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the Ig(alpha)/Ig(beta) dimer.

Membrane immunoglobulin (mIg) M and D heavy chains possess minimal (KVK) cytoplasmic tails and associate with the Ig alpha/Ig beta (CD79) dimer to achieve surface expression and antigen presentation function. In contrast, the cytoplasmic tail of mIgG is extended by 25 residues (gamma ct). We have te...

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Detalhes bibliográficos
Main Authors: Knight, A M, Lucocq, J M, Prescott, A R, Ponnambalam, S, Watts, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170008/
https://ncbi.nlm.nih.gov/pubmed/9233794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.13.3842
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