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The isomeric preference of Holliday junctions influences resolution bias by lambda integrase.
Lambda site-specific recombination proceeds by a pair of sequential strand exchanges that first generate and then resolve a Holliday junction intermediate. A family of synthetic Holliday junctions with the branch point constrained to the center of the 7 bp overlap region was used to show that resolu...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169998/ https://ncbi.nlm.nih.gov/pubmed/9218815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.12.3744 |
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