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The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response.

Immunization with protein-containing antigens results in two types of antigen-specific B cell: antibody forming cells (AFCs) producing antibody of progressively higher affinity and memory lymphocytes capable of producing high affinity antibody upon re-exposure to antigen. The issue of the inter-rela...

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Библиографические подробности
Главные авторы: Smith, K G, Light, A, Nossal, G J, Tarlinton, D M
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169918/
https://ncbi.nlm.nih.gov/pubmed/9214617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.11.2996
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