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The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response.
Immunization with protein-containing antigens results in two types of antigen-specific B cell: antibody forming cells (AFCs) producing antibody of progressively higher affinity and memory lymphocytes capable of producing high affinity antibody upon re-exposure to antigen. The issue of the inter-rela...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169918/ https://ncbi.nlm.nih.gov/pubmed/9214617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.11.2996 |
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