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The GTPase Rho has a critical regulatory role in thymus development.
The present study employs a genetic approach to explore the role of Rho GTPases in murine thymic development. Inactivation of Rho function in the thymus was achieved by thymic targeting of a transgene encoding C3 transferase from Clostridium botulinum which selectively ADP-ribosylates Rho within its...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169840/ https://ncbi.nlm.nih.gov/pubmed/9171353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2397 |
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