The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation.

The signaling pathways linking integrins to nuclear events are incompletely understood. We have examined intracellular signaling by the alpha6beta4 integrin, a laminin receptor expressed in basal keratinocytes and other cells. Ligation of alpha6beta4 in primary human keratinocytes caused tyrosine ph...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Mainiero, F, Murgia, C, Wary, K K, Curatola, A M, Pepe, A, Blumemberg, M, Westwick, J K, Der, C J, Giancotti, F G
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169837/
https://ncbi.nlm.nih.gov/pubmed/9171350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2365
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