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Translocation of the Csk homologous kinase (Chk/Hyl) controls activity of CD36-anchored Lyn tyrosine kinase in thrombin-stimulated platelets.

Chk/Hyl is a recently isolated non-receptor tyrosine kinase with greatest homology to a ubiquitous negative regulator of Src family kinases, Csk. To understand the significance of co-expression of Chk and Csk in platelets, we examined the subcellular localization of each protein. Chk, but not Csk, w...

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Autors principals: Hirao, A, Hamaguchi, I, Suda, T, Yamaguchi, N
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169835/
https://ncbi.nlm.nih.gov/pubmed/9171348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2342
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