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The linker region of the ABC-transporter Ste6 mediates ubiquitination and fast turnover of the protein.
Upon block of endocytosis, the a-factor transporter Ste6 accumulates in a ubiquitinated form at the plasma membrane. Here we show that the linker region, which connects the two homologous halves of Ste6, contains a signal which mediates ubiquitination and fast turnover of Ste6. This signal was also...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1997
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169827/ https://ncbi.nlm.nih.gov/pubmed/9171340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2251 |
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