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The protease-protected 30 kDa domain of SecA is largely inaccessible to the membrane lipid phase.
SecA binds to the inner membrane of Escherichia coli through low affinity lipid interactions or with high affinity at SecYEG, the integral domain of preprotein translocase. Upon addition of preprotein and nucleotide, a 30 kDa domain of SecYEG-bound SecA is protected from proteolysis via membrane ins...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169821/ https://ncbi.nlm.nih.gov/pubmed/9171334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.9.2188 |
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