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The gypsy insulator can function as a promoter-specific silencer in the Drosophila embryo.
The Drosophila gypsy retrotransposon disrupts gene activity by blocking the interactions of distal enhancers with target promoters. This enhancer-blocking activity is mediated by a 340 bp insulator DNA within gypsy. The insulator contains a cluster of binding sites for a zinc finger protein, suppres...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1997
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169776/ https://ncbi.nlm.nih.gov/pubmed/9130717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.7.1732 |
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