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ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling.

We have analyzed ErbB receptor interplay induced by the epidermal growth factor (EGF)-related peptides in cell lines naturally expressing the four ErbB receptors. Down-regulation of cell surface ErbB-1 or ErbB-2 by intracellular expression of specific antibodies has allowed us to delineate the role...

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Hlavní autoři: Graus-Porta, D, Beerli, R R, Daly, J M, Hynes, N E
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169769/
https://ncbi.nlm.nih.gov/pubmed/9130710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.7.1647
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