Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways.

The interferon-inducible double-stranded RNA protein kinase PKR controls protein synthesis through the phosphorylation of eukaryotic translation initiation factor (eIF)-2. In addition to its demonstrated role in translational control, several reports have suggested a transcriptional role for PKR. He...

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Main Authors: Wong, A H, Tam, N W, Yang, Y L, Cuddihy, A R, Li, S, Kirchhoff, S, Hauser, H, Decker, T, Koromilas, A E
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169727/
https://ncbi.nlm.nih.gov/pubmed/9135145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.6.1291
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