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A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E.

In the yeast Saccharomyces cerevisiae a small protein named p20 is found associated with translation initiation factor eIF4E, the mRNA cap-binding protein. We demonstrate here that p20 is a repressor of cap-dependent translation initiation. p20 shows amino acid sequence homology to a region of eIF4G...

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Autori principali: Altmann, M, Schmitz, N, Berset, C, Trachsel, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169710/
https://ncbi.nlm.nih.gov/pubmed/9118949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.5.1114
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