Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion.

We have surveyed the tandemly repeated genes encoding U2 snRNA in a diverse panel of humans. We found only two polymorphisms within the U2 repeat unit: a SacI polymorphism (alleles SacI+ or SacI-) and a CT microsatellite polymorphism (alleles CT+ or CT-). Surprisingly, individual U2 tandem arrays ar...

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Detalhes bibliográficos
Main Authors: Liao, D, Pavelitz, T, Kidd, J R, Kidd, K K, Weiner, A M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169662/
https://ncbi.nlm.nih.gov/pubmed/9034341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.3.588
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