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Cyclosporin A-sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel pathway involving a MEF2 family member.

Induction of the Epstein-Barr virus (EBV) lytic cycle by crosslinking surface immunoglobulin is inhibited by the immunosuppressants cyclosporin A (CsA) and FK506. This correlates with the ability of CsA to inhibit Ca2+-dependent transcription of the lytic cycle switch gene BZLF1. It is shown here th...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, S, Liu, P, Borras, A, Chatila, T, Speck, S H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169621/
https://ncbi.nlm.nih.gov/pubmed/9009275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.1.143
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